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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
8.18
Human Site:
S522
Identified Species:
13.85
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
S522
L
F
L
R
E
P
D
S
D
T
E
L
Q
M
E
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
E511
S
F
L
A
S
D
T
E
E
E
E
E
N
S
S
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
Dog
Lupus familis
XP_543382
1925
209302
S524
P
F
L
R
E
Q
D
S
D
T
E
L
Q
M
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
S513
P
F
L
R
E
Q
D
S
D
T
E
I
Q
M
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
Chicken
Gallus gallus
Q5F3P8
2008
223067
Q532
P
I
S
S
S
S
S
Q
L
S
P
I
P
M
Y
Frog
Xenopus laevis
Q66J90
1938
216239
H532
P
P
Y
S
S
S
S
H
Y
Q
D
V
T
P
S
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
I548
S
S
T
G
L
E
D
I
S
P
T
P
L
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
I468
P
P
P
P
P
E
E
I
D
N
W
D
E
E
E
Honey Bee
Apis mellifera
XP_395451
1406
159180
I234
E
K
K
P
E
K
K
I
E
K
E
I
K
S
E
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
I335
Q
L
P
Y
Y
N
N
I
Q
P
S
S
S
T
M
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
D510
W
D
R
R
D
R
Q
D
Y
H
S
N
K
R
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
T141
S
H
T
H
N
S
T
T
P
L
T
T
A
G
S
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
20
0
86.6
N.A.
80
N.A.
N.A.
0
6.6
0
6.6
N.A.
13.3
20
0
6.6
P-Site Similarity:
100
26.6
0
86.6
N.A.
86.6
N.A.
N.A.
0
20
13.3
13.3
N.A.
26.6
40
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
6.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
0
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
0
8
8
29
8
29
0
8
8
0
0
8
% D
% Glu:
8
0
0
0
29
15
8
8
15
8
36
8
8
8
36
% E
% Phe:
0
29
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% G
% His:
0
8
0
8
0
0
0
8
0
8
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
29
0
0
0
22
0
0
0
% I
% Lys:
0
8
8
0
0
8
8
0
0
8
0
0
15
0
0
% K
% Leu:
8
8
29
0
8
0
0
0
8
8
0
15
8
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
29
8
% M
% Asn:
0
0
0
0
8
8
8
0
0
8
0
8
8
0
8
% N
% Pro:
36
15
15
15
8
8
0
0
8
15
8
8
8
15
0
% P
% Gln:
8
0
0
0
0
15
8
8
8
8
0
0
22
0
0
% Q
% Arg:
0
0
8
29
0
8
0
0
0
0
0
0
0
8
0
% R
% Ser:
22
8
8
15
22
22
15
22
8
8
15
8
8
15
22
% S
% Thr:
0
0
15
0
0
0
15
8
0
22
15
8
8
8
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
8
8
8
0
0
0
15
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _